How Vitamins and Minerals Affect Genes

How Vitamins and Minerals Affect Genes

The daily dose of vitamins and minerals helps to strengthen health. According to the Office of Disease Prevention and Health Promotion (ODPHP), three-quarters of the US population, especially, have a diet low in vegetables, fruits, milk and fat. Genetic variation affects overall health and how the body absorbs nutrients, and genes control digestion, absorption, and how the body uses nutrients. […]

A daily dose of vitamins and minerals helps to strengthen health. According to the Office of Disease Prevention and Health Promotion (ODPHP), three-quarters of the US population, especially, have a diet low in vegetables, fruits, milk and fat. Genetic variation affects overall health and how the body absorbs nutrients, and genes control digestion, absorption, and how the body uses nutrients. Variations can change how the body processes vitamins and minerals; It can turn beneficial vitamins into harmful ones.
The right dosage of vitamins and minerals can create a life-changing effect, eliminate negative health symptoms, restore energy, increase restful sleep and even change the expression of your genes.

While genes form part of the DNA that determines the characteristics, an allele is a living DNA coding located on a chromosome and a specific form of a gene. People are different because of gene variations that can result from random mutations and mixtures inherited from parents.
If a problem gene is inherited from a parent, it is heterozygous (a copy). If both parents have the problem gene and passed it on to the child, it is homozygous (two copies). The risk increases when two copies of a gene are found. However, this does not mean that you will get a specific disease. Today, thanks to genetic testing and right-hand healthcare professionals, it is possible to help the person by making lifestyle adjustments by interpreting gene findings, to stop bad genes and to attempt to activate good genes.

Vitamins and Minerals

How Vitamins and Minerals Affect Genes? Genetic testing defines which foods are compatible with the body based on genetic variations.

These tests show a genetic predisposition to cancer and heart disease, as well as what vitamins (and dosage) are needed for optimal health.
Vitamins and minerals can change your genes. Vitamins are made up of organic molecules that function in various capacities in the body. They serve as co-factors for enzymatic reactions and are crucial to being a part of a diet. Minerals are important for diet and are necessary to support functional and structural roles. Vitamins and minerals work together to repair, restore, and turn food into energy. Lack of important components can cause significant harm to the body. For example, ancient sailors often suffered from scurvy from vitamin C depletion. Conversely, the right amount of nutrients can provide significant health benefits.
In fact, a study has been conducted on supplementing with antioxidant vitamins that prevent oxidative modification of DNA in lymphocytes of human immunodeficiency virus (HIV) infected patients. Patients were supplemented with antioxidant vitamins A, C and E or given placebo, vitamin supplementation resulted in a significant decrease in levels of all modified DNA bases compared to patients receiving placebo.

How Does Vitamins and Minerals Improve Gene Function?

Single Nucleotide Polymorphisms (SNPs) make a person’s genes (enzymes) less efficient than normal.

Variations in SNPs in the gene population affect function and, in some cases, the response to vitamins. For years, the Uniqueness Principle has been put forward, which suggests what is good for one and may not be good for the other. Therefore, it is important to adapt a customized supplement regimen to optimize genetic function. Controlling the expression of genes involves understanding what genes need for optimal health. Genes adapt to environmental factors such as stress, diet and toxins and often vary from their origins at birth.

What Vitamins and Minerals Are Beneficial to Genes?

Deficiencies in vitamins and minerals can cause DNA damage and folate, B12 There is evidence to suggest that deficiencies in vitamins B6 and C, zinc, and iron can lead to DNA damage and cancer. Nutritional deficiencies are evident in the United States and other countries. Proper supplementation (paired with improved diet) can reduce the risk of chronic disease and premature aging.
How Vitamins and Minerals Affect Genes? According to the Principles of Nutrigenetics and Nutrigenomics, the deficiency in micronutrients increases DNA replication stress and genomic imbalance, susceptibility to DNA damage caused by endogenous and environmental genotoxins, and also disables normal control of gene expression by epigenetic mechanisms.

The CBS gene needs B6. COMT gene requires magnesium.
• To regulate homocysteine ​​levels and reduce MTHFR gene variants C677T and A1298C (reduce the efficiency of folate metabolism): Folate Methylation SNPS needs more B12, folate, B6 and B2. 5465G to A and 744G to C PEMT gene variants require choline to reduce the low levels seen in premenopausal women.
• Regulates the expression of some oncogenes (cancer-causing gene): beta-carotene, retinoic acid, alpha-tocopheryl succinate and D vitamin.
Supplementing customized vitamins and minerals has a variety of health benefits, but the most important is maintaining the best possible genetic health.

Bibliography:
/health.gov/dietaryguidelines/2015/guidelines/chapter-2/current-eating-patterns-in-the-united-states/
https://themedicalbiochemistrypage.org/vitamins.php
www. sciencedirect.com/science/article/abs/pii/S0891584901008218

Author: Özlem Güvenç Ağaoğlu

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